2011年的最后一期NEJM!12月29日365卷第26期的這期新鮮NEJM,頗為給力!你絕對不能錯過!

【原始論文】

1. 高?;颊唧y關節術后的自由或限制性輸血

Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery

[評論] 聚焦輸血閾值

Transfusion Thresholds in FOCUS

2.?低分子肝素和危重患者的死亡率

Low-Molecular-Weight Heparin and Mortality in Acutely Ill Medical Patients

3.?貝伐單抗對卵巢癌的首次治療

Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer

4. 貝伐單抗治療卵巢癌的3期試驗?

A Phase 3 Trial of Bevacizumab in Ovarian Cancer

5. **慢性淋巴細胞白血病的_SF3B1_和其他新的癌基因**

SF3B1?and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

[評論]?癌癥中的RNA剪接機制的突變

Mutations in RNA Splicing Machinery in Human Cancers

6. 簡報:3例完整面部移植的患者

Three Patients with Full Facial Transplantation

【綜述】

發病機制:在健康與疾病中的前蛋白轉化酶

Mechanisms of Disease: Proprotein Convertases in Health and Disease

【MGH病例報道】

52歲男性出現乏力、感染與腎上腺增大

A 52-Year-Old Man with Weakness, Infections, and Enlarged Adrenal Glands

【基礎研究的臨床意義】

糖尿病干細胞的“移動病”

Diabetic Stem-Cell “Mobilopathy”

【觀察】

1. 臨床的版權與開放獲取

Copyright and Open Access at the Bedside(免費全文)

2. 少有人走的路

The Road Less Traveled

【臨床圖片】

1. A Head Shot?(免費全文)

2. Lichtenberg Figures(免費全文)

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