2011年的最后一期NEJM!12月29日365卷第26期的這期新鮮NEJM,頗為給力!你絕對不能錯過!
【原始論文】
1. 高?;颊唧y關節術后的自由或限制性輸血
Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery
[評論] 聚焦輸血閾值
Transfusion Thresholds in FOCUS
2.?低分子肝素和危重患者的死亡率
Low-Molecular-Weight Heparin and Mortality in Acutely Ill Medical Patients
3.?貝伐單抗對卵巢癌的首次治療
Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer
4. 貝伐單抗治療卵巢癌的3期試驗?
A Phase 3 Trial of Bevacizumab in Ovarian Cancer
5. **慢性淋巴細胞白血病的_SF3B1_和其他新的癌基因**
SF3B1?and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
[評論]?癌癥中的RNA剪接機制的突變
Mutations in RNA Splicing Machinery in Human Cancers
6. 簡報:3例完整面部移植的患者
Three Patients with Full Facial Transplantation
【綜述】
發病機制:在健康與疾病中的前蛋白轉化酶
Mechanisms of Disease: Proprotein Convertases in Health and Disease
【MGH病例報道】
52歲男性出現乏力、感染與腎上腺增大
A 52-Year-Old Man with Weakness, Infections, and Enlarged Adrenal Glands
【基礎研究的臨床意義】
糖尿病干細胞的“移動病”
Diabetic Stem-Cell “Mobilopathy”
【觀察】
1. 臨床的版權與開放獲取
Copyright and Open Access at the Bedside(免費全文)
2. 少有人走的路
【臨床圖片】
1. A Head Shot?(免費全文)
2. Lichtenberg Figures(免費全文)