八爪悅讀,創造幸福!1月19日366卷第3期的新鮮NEJM,很值得看的醫學前沿進展!

【原始論文】

1.?皮膚鱗狀細胞癌患者中接受BRAF抑制劑治療的RAS基因突變

RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors

[評論] ?環繞邊緣——BRAF抑制劑的悖論

RAF around the Edges — The Paradox of BRAF Inhibitors

2.?丙肝基因型1的抗病毒藥物的兩個初步研究

Preliminary Study of Two Antiviral Agents for Hepatitis C Genotype 1

[評論] ?丙型肝炎治療的分水嶺時刻

A Watershed Moment in the Treatment of Hepatitis C

3.?老年女性骨質疏松的骨密度測試間隔與轉型

Bone-Density Testing Interval and Transition to Osteoporosis in Older Women

4. **非上皮卵巢癌的反復DICER1基因突變**

Recurrent Somatic?DICER1?Mutations in Nonepithelial Ovarian Cancers

5.?簡報:甲狀腺激素受體的α基因突變

Brief Report: A Mutation in the Thyroid Hormone Receptor Alpha Gene

【MGH病例報道】

63歲女性出現呼吸困難及進行性的呼吸衰竭

Case 2-2012 — A 63-Year-Old Woman with Dyspnea and Rapidly Progressive Respiratory Failure

【綜述】

當前概念:冠脈搭橋術后的認知與神經系統預后

Current Concepts: Cognitive and Neurologic Outcomes after Coronary-Artery Bypass Surgery

【觀察】

1. 減輕痛苦101——止痛在美國

Alleviating Suffering 101 — Pain Relief in the United States

2. 痛苦的不公平現象——發展中國家姑息治療

Painful Inequities — Palliative Care in Developing Countries

3.?阿托伐他汀和醫療保健費用

Generic Atorvastatin and Health Care Cost(免費全文)

【臨床圖片】

1. 椎體術后的肺栓塞?Pulmonary Cement Embolism after Vertebroplasty?(免費全文)

how can i get my ex back

2.Tophaceous痛風?Tophaceous Gout(免費全文)

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